32 NOWE BADANIA KLINICZNE - aktualizacja z dnia 23.10.2019

12.05.2023

W dniu 23.10.2019 r. sfinalizowano kolejną aktualizację przewodnika po badaniach klinicznychBadX.

Poniższa tabela zawiera listę badań klinicznych, które zostały zakończone bądź zamknęły proces rekrutacji (usunięto*) oraz nowe badania, które pojawiły się właśnie na rynku (dodano*).

Lista wprowadzonych zmian jest następująca: Astma:
Dodano:
-**GB001 (**GB001 in Adult Subjects With Moderate to Severe Asthma)
-AAPABA(Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis)
-MTPS9579A(A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients With Asthma Requiring Inhaled Corticosteroids and a Second Controller)
Usunięto:
*-***QMF149vTwisthaler(Study of QMF149 (150/80 µg) Compared With MF Twisthaler® (200 µg) in Patients With Asthma)
-MiSEAP(Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients)
-DESTINATION(Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma)
-RAISe(Response of the Airway in Sinusitis and Asthma)
-PATH-HOME(Tezepelumab Home Use Study)
**-MDL AZD7594 (**A Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD7594 Administered Once Daily by Inhalation in Asthmatic Subjects)
-VOYAGE(Evaluation of Dupilumab in Children With Uncontrolled Asthma)Atopowe zapalenie skóry:
Dodano:
-JADE TEEN(JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis)
-NemoAtD 2(Efficacy and Safety of Nemolizumab in Subjects With Moderate-to-Severe Atopic Dermatitis)
Usunięto:
-BREEZE-AD4(A Long-term Study of Baricitinib (LY3009104) With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis That Are Not Controlled With Cyclosporine or for Those Who Cannot Take Oral Cyclosporine Because it is Not Medically Advisable)
-BREEZE-AD7(A Study of Baricitinib (LY3009104) in Combination With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis)
-JADE Mono-2(Study Evaluating Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis)Choroba Alzheimera:
Dodano:
-GAIN(GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease)
-RO7105705(A Study of RO7105705 in Patients With Moderate Alzheimer's Disease)
Usunięto:
-BI 425809(BI 425809 in Patients With Cognitive Impairment Due to Alzheimer's Disease)
-COGNITE(Safety and Efficacy Study of ALZT-OP1 in Subjects With Evidence of Early Alzheimer's Disease)
-MissionAD1(A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease)
-MissionAD2(A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease)
-PimaDemPsy(Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis)
-TANGO(Phase 2 Study of BIIB092 in Participants With Early Alzheimer's Disease)Choroba Leśniowskiego-Crohna:
Dodano:
-PRISM (A Study Evaluating Participants With Moderately to Severely Active Crohn's Disease)
-SHR0302 CD(A Phase II Study in Patients With Moderate to Severe Active Crohn's Disease)
-E6011 CD(A Study of E6011 in Participants With Active Crohn's Disease)
Usunięto:
-EtroPedCD(A Phase I Study Of Etrolizumab Followed By Open-Label Extension And Safety Monitoring In Pediatric Patients With Moderate To Severe Ulcerative Colitis Or Moderate To Severe Crohn's Disease)Choroba zwyrodnieniowa stawów:
Dodano:
-FasinumabOsteo(Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee)
Usunięto:
-FACT LTS & OA(Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip)Cukrzyca:
Dodano:
-ProGasMet(Probiotics in Metformin Intolerant Patients With Type 2 Diabetes)
-SUSTAIN FORTE(A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes)
-SURPASS-5(A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin)
-FLOW Db(A Research Study to See How Semaglutide Works Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease)
-Granexin(A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer)
-RedStroke Db(RedStroke - Reducing Europe's Stroke Incidence)
-GRACE Db(A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome)
Usunięto:
-AMPLITUDE-M(Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise)
-287/Glarg(A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before)
-Insulin 287(A Research Study to Compare Insulin 287 Once a Week to Insulin Glargine (100 Units/mL) Once a Day in People With Type 2 Diabetes)
-PRO Solo(Participant-Reported Outcomes With the Accu-Chek® Solo Micropump System)Jaskra:
Dodano:
-BimaSR/Laser(Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension)Migotanie przedsionków:
Dodano:
-ENVISAGE-TAVI AF(Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation)
-Watchman FLX (Eur)(Watchman FLX Left Atrial Appendage Closure Device Post Approval Study ( Europe Only))
-ASAP-TOO(Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation)Nadciśnienie płucne:
Dodano:
-EXPERT-BPA(Hemodynamic Effects of BPA at Rest and During Exercise in CTEPH)
-SELECT PH(A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery)
-RaliPH(A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients)
Usunięto:
-InShape2(Early Non-invasive Detection of CTEPH After Pulmonary Embolism)
-REPLACE(Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy)Nadciśnienie tętnicze:
Usunięto:
-ASSECURE(Cardiovascular Response to Exercise in Hypertension)
-Moderato(Moderato System in Patients With Hypertension)
-ModeratoV.1.1(Moderato System: A Double-Blind Randomized Trial Ver 1.1)
-PRECIOUS(Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine)Niealkoholowa stłuszczeniowa choroba wątroby:
Usunięto:
-Kids4LIFe(Assessing Kids for Liver Inflammation and Fibrosis Using Non-invasive MRI)
-REGENERATE(Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment)Otyłość:
Usunięto:
-MicroPCOS(Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients)
-ProSupp (Effect of Oral Supplementation With Probiotics)Przewlekła choroba nerek:
Usunięto:
-****ASCEND-ID(Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis)
-Dapa-CKD (A Study to Evaluate the Effect of Dapagliflozin on Renal Outcomes and Cardiovascular Mortality in Patients With Chronic Kidney Disease)
-KALM-2(CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus)
-PRO2TECT(Efficacy and Safety Study to Evaluate Vadadustat for the Correction of Anemia in Subjects With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD))Rak jelita grubego:
Dodano:
-SOLSTICE(Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy)
-PIPACRegis(International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC))RZS:
Usunięto:
-TvTNF(Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis)Stwardnienie rozsiane:
Dodano:
-EVOLUTION RMS1(Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS))
-O'HAND(A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis)
Usunięto:
-ASCLEPIOS II(Efficacy and Safety of Ofatumumab Compared to Teriflunomide in Patients With Relapsing Multiple Sclerosis)
-CLARIFY MS(Evaluation of Quality of Life (QoL) in Subjects With Highly Active Relapsing Multiple Sclerosis (MS))
-EVOLVE-MS-1(A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS))
-HAMS(Evaluation of the Onset of Action in Highly Active Multiple Sclerosis (MS))
-OPTIMUM-LT(Long-term Extension to Study AC-058B301 to Investigate Safety, Tolerability and Disease Control of Ponesimod 20 mg in Patients With Relapsing Multiple Sclerosis)Toczeń rumieniowaty układowy:
Dodano:
-VIB-SLE(A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis)
Usunięto:
-****BI 655064 SLE(Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis)
-CC-220 SLE(A Study to Evaluate the Efficacy and Safety of CC-220 in Subjects With Active Systemic Lupus Erythematosus)
-M2951 II(A Phase II Study of M2951 in Systemic Lupus Erythematosus (SLE))
-TULIP-LN1(Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis)Wrzodziejące zapalenie jelita grubego:
Dodano:
-GSK2831781 UC(Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis)
-QUASAR(A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis)
Usunięto:
-CONDUCT(The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis)